The injury - if confirmed - would be a devastating blow to the 6-6 Broncos, who've won three straight games to get back in the AFC playoff race.
Sanders has been enjoying another strong year in Denver, with 71 receptions for 868 yards and four touchdowns. He eclipsed the 1,000-yard mark in three of the last four seasons.
The 31-year-old has one year left on his contract, but his 2019 salary isn't guaranteed.
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