Fournette has been sidelined by a hamstring injury for all but two games this season. He most recently played against the New York Jets in Week 4, racking up 11 carries for 30 yards and one reception for 5 yards before another hamstring injury forced him to leave the game.
T.J. Yeldon is the Jaguars' leading rusher this season. He's gained 334 yards on 81 carries but has scored just one touchdown with one lost fumble. He's added 346 yards and four touchdowns on 37 receptions.
The Jaguars, 3-5, rank 24th in the NFL with 95 rushing yards per game after leading the league in that category last season.